Assessment of drug discontinuation among adult patients who are taking antiretroviral treatment at Yeka Sub-City Woreda 9 and 10 health centers Addis Ababa, Ethiopia

Background:  Antiretroviral  therapy  has  led  to  a  substantial  reduction  in  HIV-associated  morbidity and  mortality.  Efficacy  of  antiretroviral  treatment  in  HIV/AIDS  is  showing  inhibition  of  viral replication and reduction of viral load to a point where viral particles are undetectable in the blood of infected individuals. This has led to the realization that HIV/AIDS is a chronic illness.

Objective: The main objective of this study was to assess drug discontinuation patients who are taking antiretroviral treatment at yeka sub-city woreda 9 and 10 Addis Ababa Ethiopia.

Methods: A cross-sectional descriptive study was employed using quantitative approach to assess drug discontinuation  among  patients  who  are  taking  antiretroviral  treatment  among  HIV/AIDS  infected persons.

Result: At the end of one month study period 219 patients from the total 620 returned to the pharmacy to  refill  their  medication  were  interviewed  and  the  drug  discontinuation  to  ARV  medication  was  27(12.3)% of all prescribed doses. Conclusion  and  Recommendation:  Drug  discontinuation  to  antiretroviral  regimen  is  critical,  patient must  take  95  percent  of  the  prescribed  pills  to  achieve  an  80%  of  the  likelihood  of  HIV  suppression below 50 copies per ml, regarding to the present study the drug discontinuation was 12.3%.

To more know more about the article: https://www.alliedacademies.org/allied-journal-of-medical-research/archive/aaajmr-volume-2-issue-1-year-2018.html

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